a bid submitted by a bidder as an alternative bid or offer along with the main bid alternative bids are frequently in response to a requirement specified in the bid documents sometimes bidders submit alternative bids voluntarily
Báo cáo khoa học: Irreversible cross-linking of heme to the distal tryptophan of stromal ascorbate peroxidase in response to rapid inactivation by H2O2 ppt
... preventing it from interacting with ascorbate Table Steady-state kinetic parameters of APXs To investigate the role of Trp35 in the cross-link and the inactivation of APX by H2O2, we created a mutant ... tsAPX and tsAPXW35F appeared as single bands when separated by SDS ⁄ PAGE (data not shown) O2-free APX solution was prepared by passing APX in 10 mm potassium phosphate, pH 7.0, mm EDTA, mm ascorbate, ... contaminating apoprotein (data not shown) These results strongly support the idea that the formation of the cross-link is at least part of the reason for the rapid inactivation of tsAPX In these...
- 8
- 241
- 0
The phenomenon of evaporative cooling from a humid surface as an alternative method for air-conditioning
... On the other hand, to cool air in summer, mainly in hot and dry climates, the process of evaporative or adiabatic cooling appears as an alternative There are many systems that can operate as ... stream and transfer it to the secondary air in the evaporative cooling process They can be made either of metal or plastic and must easily conduct heat, maintain the two streams separated and ... Legionnaire’s disease The bacteriological contamination, mainly by legionnaire’s bacteria, has become the main disadvantage of the evaporative cooling systems Therefore, this implies that in many cases...
- 28
- 652
- 0
Báo cáo y học: "Cost-effectiveness of micafungin as an alternative to fluconazole empiric treatment of suspected ICU-acquired candidemia among patients with sepsis: a model simulatio" ppsx
... consultants to and SK is an employee of Astellas SK is a stock holder in Astellas Pharma US, Inc, the manufacturer of micafungin AFS and MDZ have received research and consulting funding, and SK ... combined with a large decrement in the remaining quality of life, the cost remains $50,722 per QALY In the worst-case analysis, with all of the inputs skewed maximally against MIC, the incremental ... scenario, with all inputs biased against the empiric MIC vs FLU strategy Input Candidemia as % BSI CK/CG as % candidemia Candidemia attributable mortality Candidemia mortality reduction if treated...
- 11
- 254
- 0
Báo cáo khoa học: Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics pptx
... cells with the mTOR inhibitor, rapamycin, increased BIM expression and overcame RAS-dependent survival signals to promote cell death, arguing that mTOR was an important survival signal that acted, ... imatinib therapy have point mutations in the BCR–ABL kinase domain, including the T315I gatekeeper mutation that impairs imatinib binding [58,59] Accordingly, new therapies are being tested and ... signal transducer and activator of transcription (JAK-STAT) pathway, to promote proliferation, survival and transformation [56,57] The importance of the BCR–ABL tyrosine kinase in the survival...
- 13
- 453
- 0
báo cáo hóa học: " The agreement between workers and within workers in regard to occupational exposure to mercury in dental practice assessed from a questionnaire and an interview" potx
... copper amalgam, performed manual mixing in a mortar, and used a Dentomat Taking the answers from the interview on these questions as the true answer and comparing this to the similar answers from the ... nurses and the dentist in regard to the questions as to whether the amalgam was soft or firm As it was the dental nurses in the clinics who filled the Dentomat and who prepared the amalgam for use ... of the study and the drafting of the manuscript KS has in addition performed the analyses Both authors have read and approved the final manuscript Competing interests The authors declare that they...
- 8
- 422
- 0
Báo cáo y học: "Childhood adversity, mental ill-health and aggressive behavior in an African orphanage: Changes in response to trauma-focused therapy and the implementation of a new instructional system" ppt
... (range - 16) at t1 and M = 9.16 years (range - 16) at t2 The Tanzanian and German board of the organization managing the orphanage gave their consent and ethical approval Materials The interview ... periods of assessment, interviewers and translators stayed in the orphanage and shared the meals with the children and played with them in their free time Analyses All variables except one met the preconditions ... Although many orphanages exist and care for OVC, a detailed evaluation of education and care in orphanages lacks in most cases However, some studies have examined aspects of how orphanages could...
- 9
- 405
- 0
Tài liệu FOCUS ON DATA XMLPULL AS AN ALTERNATIVE TO DOM & SAX doc
... create, alter and drop database entities and insert data into a database Reverse engineering database schemas from existing databases is also supported The format is compatible with both PEAR::MDB ... variable instead of the database, which is a lot quicker A call to setField() can update the member variable, not the database— again, far quicker, and safe When all the changes are made, a call ... define(DATABASE_HOSTNAME, “localhost”); define(DATABASE_BASENAME, “phpa”); $GLOBALS[“db”] = pg_Connect(“user=’” DATABASE_USERNAME “‘ password=’” DATABASE_PASSWORD “‘ dbname=’” DATABASE_BASENAME...
- 63
- 496
- 1
Tài liệu Báo cáo khoa học: Analyzing changes of chromatin-bound replication proteins occurring in response to and after release from a hypoxic block of replicon initiation in T24 cells pptx
... and then gradually increased up to 10 h, when maximal incorporation was attained This was followed by a decrease Under hypoxia, in contrast, incorporation decreased to a background level during ... that after medium exchange and further normoxic gassing first mitotic cells appear after about 13 h, their number increases within the next h and decreases again at longer incubation A similar increase ... DNA was detectable and the amount of PCNA not extractable by Triton buffer was high in the same cells These results clearly show that the PCNA staining is colocated with the BrdU staining and...
- 11
- 610
- 0
Bank Behavior in Response to Basel III: A Cross-Country Analysis doc
... greater As a result, an increase in capital leads to a decrease in the demand for future capital, K’ An increase in the marginal cost of loans leads the bank to forecast a higher marginal cost in the ... deposits and the provision for loan losses would lead to an increase in the loan rate, since the marginal cost of loans would increase The marginal cost also increases with an increase in RAROC This ... that an increase in the loan rate would reduce the demand for loans, and hence loans issued by the bank On the other hand, an increase in economic activity is expected to increase the demand for...
- 35
- 269
- 0
báo cáo hóa học:" Identifying alemtuzumab as an anti-myeloid cell antiangiogenic therapy for the treatment of ovarian cancer" pdf
... Factor Competing interests The University of Michigan and RJB have submitted a patent regarding the use of Alemtuzumab as an anti-angiogenic agent in ovarian cancer This was submitted after the ... and 7-Amino Actinomycin D (7-AAD BD Pharmingen) and analyzed by FACS Once again to assess cellular viability an aliquot of cells which receive no treatment were maintained at 37C in the ascites ... 6B and 6C) Finally, we used an orthotopic intraperitoneal model of ovarian cancer to assess the impact of therapy on animal survival In this model animal reproducibly develop tumor associated ascites...
- 14
- 728
- 0
Báo cáo hóa học: "Error Sign Feedback as an Alternative to Pilots for the Tracking of FEXT Transfer Functions in Downstream VDSL" pptx
... the noise variances at the various CPEs are the same The analysis does not provide any justification for the assumption that the estimation error variances are equal within one line i as (53) only ... (or decreasing noise variance) It can also be seen that the gain is indeed higher than for reasonable cases: it does not seem reasonable to allow the interference, which is due to changes in the ... limited amount of information about the signal received at the CPEs Now thanks to the coordination at the CO, all symbols transmitted to all different lines are known, and that additional information...
- 14
- 601
- 0
Báo cáo khoa học: " Livelihood Strtategies of Peri-Urban Households in Response to Rural Urban Linkages: A Case Study in a Peri-Urban Area of Hanoi, Vietnam" ppt
... Publishing House Li, Tana 1996 “Peasants on the Move: RuralUrban Migration in the Hanoi Region.” 30 Occasional Paper, No 91 Singapore: Institute of Southeast Asian Studies Salant, P., and D .A Dillman ... agricultural land area of the households and their livelihood strategy, agricultural land area per capita as well as agricultural land area per laborer of the households have a relationship with their ... of the commune The data gained from the survey was utilized to describe the urban linkages of the local households with the Hanoi urban area In addition, the data was also used to examine relations...
- 14
- 405
- 0
Báo cáo khoa học: "Osmotic adjustment in Pinus pinaster cuttings in response to a soil drying cycle" pptx
... ΨΠ, and the ΨΠ value varie with both investigator and species, summarize the effects of the variations in the ln RWC/(–ln (–ΨΠ)) relationship, and are calculated by many authors as an indicator ... and A = [21] When the increase in solute concentration was more than that resulting from a decrease in water content (the passive component), then osmoregulation was active and A was less than ... resistance for annual and woody plants [7, 22, 26, 32, 33] Reduced osmotic potential allows the plant to maintain turgor, and therefore turgor-dependent processes such as cell expansion and stomatal...
- 5
- 291
- 0
Báo cáo toán học: "SIMWAL: A structural-functional model simulating single walnut tree growth in response to climate and pruning" docx
... transport rate, and respiration rate) are linearly related to leaf nitrogen content on an area basis Na [41] Na is correlated to the actual time-integrated leaf irradiance as [40]: Na ... walnut are given in [41] Carbon losses are split into growth respiration R g (associated with the synthesis of new biomass) and maintenance respiration Rm (associated with the maintenance and turn-over ... is the amount of carbon that has actually been incorporated in the organ at t – according to assimilate availability This formulation relies on the observation that the activity of the enzymatic...
- 15
- 227
- 0
Báo cáo y học: "Onset of efficacy with acute long-acting injectable paliperidone palmitate treatment in markedly to severely ill patients with schizophrenia: post hoc analysis of a randomized, double-blind clinical trial" doc
... model, with treatment and country as factors and baseline score as a covariate Changes from baseline are presented as leastsquares (LS) means and standard errors (SEs) Change from baseline in PANSS ... PANSS total score was further evaluated for all subjects using a mixed model with time, country, treatment, and treatment -by- time interaction as factors and baseline value as a covariate An unstructured ... Helsinki and that are consistent with good clinical practice and applicable regulatory requirements The original study protocol was reviewed and approved by an independent ethics committee or an institutional...
- 10
- 442
- 0
Báo cáo y học: "volution of an adenocarcinoma in response to selection by targeted kinase inhibitors" potx
... presence in the tongue may indicate an origin in a minor salivary gland Adenocarcinomas of the tongue are rare and represent the minority (20 to 25%) of the salivary gland tumors affecting the tongue ... Auris Nasus Larynx 2004, 31:85-88 Tanaka T, Watanabe T, Kazama Y, Tanaka J, Kanazawa T, Kazama S, Nagawa H: Chromosome 18q deletion and Smad4 protein inactivation correlate with liver metastasis: ... to activate Ras and its signaling pathways [30] Aberrations leading to increased activation of the PI3K/AKT pathway are common in human cancers and are reviewed in [31] Inactivating mutations and...
- 12
- 301
- 0
Báo cáo y học: "tromal Vascular Fraction Transplantation as an Alternative Therapy for Ischemic Heart Failure: Anti-inflammatory Role" doc
... statistical analysis Analysis of Fibrotic Area The percentage of fibrotic area in the infarct and periinfarct zone was calculated in each heart using the image analysis software (Scion Image Beta 4.02 ... transplantation compared to those of BM-MNC transplantation and the anti-inflammatory role of transplanted cells after implanted into a rat chronic myocardial infarction Survived donor cells in ... Komeda M: Administration of control-released hepatocyte growth factor enhances the efficacy of skeletal myoblast transplantation in rat infarcted hearts by greatly increasing both quantity and quality...
- 10
- 388
- 0
Báo cáo y học: "Lepirudin as an alternative to “heparin allergy” during cardiopulmonary bypas" pot
... renal clearance, increases bleeding diathesis and it is also antigenic It is almost the same size molecule as both protamine and aprotinin Both of these agents are known for their antigenicity As ... systemically anticoagulate a patient during CPB, instead of heparin has important implications It renders the standard ACT testing, inadequate Moreover, lepirudin cannot be reversed, as with the heparin-protamine ... unavailability in standard hospital laboratories Furthermore, the unavailability of a reversing agent greatly increases the potential for peri-operative bleeding These difficulties can be addressed...
- 5
- 313
- 0
Báo cáo y học: "Background: Percutaneous tracheostomy (PT) has gained an increasing acceptance as an alternative to the conventional surgical tracheostomy (ST). In experienced hands, and with proper patient selection, it is safe, easy and quick." docx
... the needle directed cranially and the tracheal cannula inserted with a pull-through technique along the orotracheal route The cannula is then rotated downward using a plastic obturator The main ... them are minor With proper patient selection, operator experience and attention to detail, complication rates can be reduced that may have an influence on late complications An important advantage ... percutaneous dilatational tracheostomy Figures on late complications after decannulation, including tracheal stenosis, hoarseness and tracheomalacia, are difficult to analyze since the criteria applied...
- 6
- 342
- 0
Báo cáo khoa học: "RAGE: Exacting a toll on the host in response to polymicrobial sepsis and Listeria monocytogenes" pps
... failure to clear the organism [6,7] In the initial phase of infection, Listeria binds to splenic macrophages and is internalized; Listeria produces products that activate nuclear factor-kappa ... Zeng S, Yan SF, Ramasamy R, Emond J, Clynes R, Schmidt AM: Receptor for advanced glycation end products (RAGE) in a dash to the rescue: inflammatory signals gone awry in the primal response to stress ... growth and metastases Nature 2000, 405:354-360 13 Wang H, Bloom O, Zhang M, Vishnubhakat JM, Ombrellino M, Che J, Frazier A, Yang H, Ivanova S, Borovikova L, et al.: HMG-1 as a late mediator of...
- 3
- 286
- 0
Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng 9 tr 25